Table 4 Recent research and development related to Rubus species

Rubus idaeus

Acid, alkaline, and enzymatic hydrolysis to improve the release of phenolic compounds

All methods significantly improve the isolation of phenolics while acid hydrolysis was the most efficient

[97]

Rubus fruticosus

Extraction of antioxidants, and microencapsulation with maltodextrin by spray dryer to check stability at different pH

Maltodextrin was found to be efficient in reducing the anthocyanin loss against increased pH, greater stability was observed at lower pH. A reduction in the percentage loss of antioxidants was observed using water for the extraction

[98]

Rubus humulifolius

Cryopreservation protocol for critically endangered R. humulifolius in Finland

A method of cryopreservation was developed by incorporating abscisic acid resulting in enhancement of cryopreservation for critically endangered R.humulifolius

[94]

Rubus fairholmianus

Synthesis of zinc oxide nanoparticles using R. fairholmianus root extract

The nanoparticles exhibited strong antimicrobial activity against Staphylococcus aureus

[95]

Rubus species

Genome sequencing

8 new chloroplast genomes were obtained, which might be helpful in phylogenic analysis of the genus

[99]

Rubus species

Three methods (spray-drying, freeze-drying, and ionic gelation) were used for microencapsulation of blackberry pomace and evaluated for stability in the absence/presence of light

Spray-dried microcapsules had the highest stability and bioavailability of anthocyanins in yogurt formulation, suggesting the potential for high-value food products

[93]

Rubus corchorifolius

Inhibitory activity assay using raspberry leaf-tea extract, molecular docking studies

Inhibition of α-glucosidase and α-amylase, the ethanolic extract improved glucose consumption of 3 T-3L1 cells

[100]

Rubus idaeus

Homeopathically prepared Rubus idaeus was studied for the treatment of cervical cancer using viability, proliferation, and cytotoxicity, assay with laser treatment in HeLa cells

Rubus idaeus extract (D3) able to reduce cellular viability, combined with laser showed an increase in adenosine triphosphate (ATP) and lactate dehydrogenase (LDH) levels

[101]

Rubus ellipticus

Actinomycetota isolated from the rhizospheres of two (R. ellipticus, Ageratina riparia) plants for their antimicrobial and plant growth-promoting activities

Plant-associated actinomycetes show potential as bioinoculants for increased crop productivity and food security

[105]

Rubus ellipticus

Synthesis and characterization of Cu₂O nanoparticles using green nanotechnology

The nanoparticles show good antimicrobial and anticancer properties with low toxicity, indicating the potential in the pharma and food industry

[96]

Rubus occidentalis and Rubus parvifolius

Development of interspecific hybrids using simple sequence repeat markers and colchicine treatments

Successful development of tetraploid providing a new genetic resource for environmental adaptability

[92]