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Table 4 Effect of different cotton extracts and gossypin on percent carrageenan-induced paw edema (E%):

From: A comprehensive tool in recycling plant-waste of Gossypium barbadense L agricultural and industrial waste extracts containing gossypin and gossypol: hepatoprotective, anti-inflammatory and antioxidant effects

Groups

  

1st h

2nd h

3rd h

4th h

Control

43.55 ± 2.2

48.82 ± 4.56

51.25 ± 3.89

58.66 ± 3.40

Indomethacin (10 mg/kg)

28.01* ± 2.62

37.74* ± 2.35

38.00* ± 3.24

33.56* ± 1.04

Gossypin (10 mg/kg)

29.89* ± 1.98

36.28* ± 3.51

29.13* ± 1.06

27.66* ± 1.92

EtOAc (100 mg/kg)

38.99 ± 3.19

43.57 ± 2.80

49.33 ± 0.86

54.17 ± 2.76

EtOAc (200 mg/kg)

42.66 ± 1.41

48.86 ± 2.2

49.58 ± 1.4

39.63* ± 3.16

Total extract (100 mg/kg)

45.47 ± 1.70

65.96 ± 5.37

66.84 ± 2.03

56.42 ± 4.44

Total extract (200 mg/kg)

40.95 ± 1.55

43.42 ± 2.39

49.52 ± 3.74

50.62 ± 4.35

Industrial 100 mg/kg)

48.76 ± 2.94

49.23 ± 1.39

54.57 ± 3.21

47.51* ± 3.09

Industrial (200 mg/kg)

35.01* ± 1.20

39.80* ± 3.51

40.06* ± 2.04

37.99* ± 2.48

CHCl3 (100 mg/kg)

26.27* ± 0.58

35.87* ± 2.44

40.05* ± 1.59

30.67* ± 2.26

CHCl3 (200 mg/kg)

27.12* ± 1.62

33.39* ± 1.11

41.72* ± 0.48

29.16* ± 1.06

  1. Every value corresponds to the mean% volume of paw edoema (E%) plus SEM (n = 6). One-way ANOVA was used for statistical analysis, and Tukey's post hoc test was then performed. Changes recorded in paw diameter for each group (at t h) from its parallel basal value (at 0 h) were compared to the control group.* Significantly different from the control group (p < 0.05) at the relevant time interval. EtOAc: ethyl acetate; CHCl3: chloroform