Recent achievements obtained by chloroplast transformation

Table 4 Vaccine antigens and biopharmaceuticals engineered via chloroplast genome of higher plants

Traits	Gene	Expression	Host plant	References
HIV/AIDS	gp120, gp41	16 μg g⁻¹ FW	Tobacco	[70]
Human papiloma virus	GUS-E7	3–4% TSB	Tobacco	[71]
Polio virus	CTB-VP1	4–5% TSP	Tobacco	[72]
Tuberculosis antigens	CTB-SAT6CTB-Mtb72F	7.5% TSP	Tobacco	[73]
Tuberculosis antigens	CTB-ESAT6	0.75% TSP	Lettuce	[73]
Bacterial	Pa	2.5–4% TSP	Tobacco	[74]
Dengue virus	EDIII	0.8–1.6 TSP	Tobacco	[75]
Bacterial phage lytic `protein	plyGBS	>70% TSP	Tobacco	[76]
Pompe disease	CTB-GAA	0.1–0.2 TLP	Tobacco	[77]
Thioredoxin 1	hTx1	15 TSP	Lettuce	[78]
Insulin liken growth factors	IGF-1n	32% TSP	Tobacco	[79]
Endolysin Cpl-1	Cpl-1	10% TSP	Tobacco	[80]
Interferon-α2b(IFN-α2b)	IFN-a2b	21% TSP	Tobacco	[81]
Basic fibroblast growth factor (bFGF)	bFGF	0.1% TSP	Tobacco	[82]

ISSN: 1746-4811