Fig. 1

Axonometric digital view and side view of the printed chamber. A represents the different parts of the diffusion chamber in an axonometric view and B represents a printed 3D chamber. In image A the four parts of the chamber show the inside contours of the different parts of the chamber. Sampling port canals (black arrow) can be seen as a thin horizontal line towards in the larger cylindrical section in the donor and receiver chamber from the outside. The leaf like diagram between the donor and middle chamber is an artistic representation of cuticular membrane. Image B represents a completely printed diffusion chamber printed with ABS (ivory) P430 thermoplastic. Image not to scale.