Skip to main content

Table 4 Overview of strengths and weaknesses of the applied methods on different levels

From: High-throughput estimation of allele frequencies using combined pooled-population sequencing and haplotype-based data processing

  MACE GBS WGS
Costs Med Low High
Genes covered Yes Partly Yes
Level RNA DNA DNA
SNP count Low Med High
Coverage Varying Med Low
Genome representation Biased Biased All
Sampling error High Low Low
  1. MACE transcriptome sequencing, GBS enzyme-based genotyping by sequencing, WGS whole-genome resequencing (med = medium)