A cautionary note on the use of chromosome conformation capture in plants

Table 1 Overview of existing and recently developed 3C-based methods

Ligation based chromatin capture method	Application	References
qPCR-based 3C	One-to-one	[23, 24]
3C-seq, 4C	One-to-all	[59, 60]
5C	Many-to-many	[61]
ChIA-PET	Many-to-many	[62]
Multiplex 3C-seq	Many-to-all	[63, 64]
HiCap,CHi-C	Many-to-all	[65,66,67]
Capture-C	Many-to-all	[68]
T2C	Many-to-all	[69]
Hi-C, Dnase Hi-C, Micro-C, Micro-CXL,	All-to-all	[67, 70,71,72,73]
TCC	All-to-all	[74]

ISSN: 1746-4811