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Table 4 Vaccine antigens and biopharmaceuticals engineered via chloroplast genome of higher plants

From: Recent achievements obtained by chloroplast transformation

Traits Gene Expression Host plant References
HIV/AIDS gp120, gp41 16 μg g−1 FW Tobacco [70]
Human papiloma virus GUS-E7 3–4% TSB Tobacco [71]
Polio virus CTB-VP1 4–5% TSP Tobacco [72]
Tuberculosis antigens CTB-SAT6CTB-Mtb72F 7.5% TSP Tobacco [73]
CTB-ESAT6 0.75% TSP Lettuce [73]
Bacterial Pa 2.5–4% TSP Tobacco [74]
Dengue virus EDIII 0.8–1.6 TSP Tobacco [75]
Bacterial phage lytic `protein plyGBS >70% TSP Tobacco [76]
Pompe disease CTB-GAA 0.1–0.2 TLP Tobacco [77]
Thioredoxin 1 hTx1 15 TSP Lettuce [78]
Insulin liken growth factors IGF-1n 32% TSP Tobacco [79]
Endolysin Cpl-1 Cpl-1 10% TSP Tobacco [80]
Interferon-α2b(IFN-α2b) IFN-a2b 21% TSP Tobacco [81]
Basic fibroblast growth factor (bFGF) bFGF 0.1% TSP Tobacco [82]