Figure 2
From: The advantages and limitations of trait analysis with GWAS: a review
Synthetic association due to genetic heterogeneity. a) A theoretical phylogenetic tree of three individuals upon which three mutations occur. The two most recent mutations (stars) cause a change in phenotype (red fruit). b) The older blue mutation has no affect on fruit colour, but is in perfect correlation with the trait. Neither causative mutation are very good predictors of the phenotype.